St. Louis, Missouri is a beautiful city located along the Mississippi River. The city was founded in 1765. St. Louis is home to many significant landmarks, attractions, and destinations within the Mississippi region. Apart from the traditional daytime activities. the city of St. Louis also features a fabulous nightlife scene.
The neighborhoods in this beautiful city feature live DJs and music performances, great cocktails, comedy theaters, and casinos that you can visit during your night out. Have you ever enjoyed cold beer, cocktails, or wine with your friends while listening to cool music and having spectacular views of the city and the sky at night? A visit to the rooftop nightlife spots in this city will give you a chance during your night out. A night out in the nightlife districts in St. Louis is livelier, just like in other great nightlife destinations such as Paris, Bangkok, Tokyo, and many more. Should you be in the Mississippi River region, you want a great, thrilling, and memorable night out experience, whether alone or with friends. It would be best if you never failed to visit the impressive nightlife districts in St. Louis, Missouri.
Here are the best ten nightlife districts in St. Louis, Missouri that visiting will ensure you have a memorable night out experience.
# 10 – Shaw
Whether you are into live music or love tasty food, this nightlife district is a great place to visit for a memorable night out experience. This neighborhood also features great venues with an eclectic setting and fireplaces. There are fantastic cafés like Venice Café with an impressive artistic vibe that you can go dining in during your night out. This neighborhood’s other unique nightlife spots include La Onda, Gaslight Studio & Lounge, and Sasha’s on Shaw.
# 9 – The Hill
There is no better neighborhood to visit than The Hill if you are into Mexican, Peruvian and Italian cuisines. You will not be disappointed by visiting the multiple restaurants located in strategic locations in this neighborhood during any day and night. As the daylight turns to a night, there are multiple venues in this nightlife district that makes it more liver and fun. There are impressive and thrilling nightlife venues with live piano music, karaoke, and live music performances. Additionally, you may find your favorite Mexican, Peruvian or Italian musician performing in one of the nightlife venues in this neighborhood during your night out. Some of the great venues in this nightlife district that you should never miss visiting during your night out include Oliva on the Hill, The Heavy Anchor, Palomino Lounge, and Parlor.
# 8 – Maryland Heights
Our top nightlife districts in St. Louis, Missouri would not be complete without visiting Maryland Heights, especially if you like gambling. This neighborhood is home to the Hollywood casino Amphitheaters that you can visit. Additionally, there are multiple bars, live music, and comedy clubs that visiting will make your night out thrilling. Suppose you want to keep yourself entertained by laughing during your night out with friends while in this neighborhood, you should head to Helium Comedy Club. You can sip your beer and watch your favorite team live in action by visiting Hotshots Sports Bar & Grill during the sports season.
You can enjoy a cold beer with friends with live music performances at Creve Coeur Lakehouse Bar & Grill. If you want live DJs and music performances in this neighborhood during your night out, you should head to Boogie Nights. This neighborhood’s other nightlife venues include Backstreet Jazz & Blues Club, Westport Social, Trainwreck Saloon Westport, and many more.
# 7 – Laclede’s Landing
Continuing with our top ten list is a night out at Laclede’s Landing. This nightlife district is also home to unique nightlife venues that will make your night out there memorable. There are multiple restaurants, bars, live music venues in Laclede’s Landing that make it very lively at night. Initially, this beautiful neighborhood was a hub for manufacturing, warehousing, and shipping. However, this has changed, and it features the best collection of jazz, blues, and dance clubs. While in this nightlife district, you can start your night out by visiting Morgan Street Brewery, where you will find gourmet pizzas, kinds of pasta, burgers, duck cakes, red snapper hash, and orange habañero baby back ribs featured in their menu.
Additionally, you may get a chance to sip a variety of handcrafted beers and ales brewed in this same nightlife venue. You can get entertained by great music and hilarious comedy while singing and dancing at Big Bag. You should never miss visiting other thrilling nightlife venues for a memorable night out experience in this nightlife district, such as jazz at the Bistro, The Pageant, and Blueberry Hill.
# 6 – Soulard
Are you a night out enthusiast and in a celebratory mood? Well, you will not be disappointed while in Soulard. This nightlife district also features some of the best nightlife venues in the region. This is one of the neighborhoods where you will find various venues hosting live music performances seven nights a week. During the day, you can spend your time understanding the culture of the region by visiting the oldest farmer’s market west of the Mississippi. As the daylight comes to an end, dozens of nightlife spots make this neighborhood lively and bring a celebratory mood.
Additionally, you can go late-night dining in multiple destinations during your night out. You can pass by the late-night food venues in this neighborhood to catch a bite when hungry before hoping in the bars, pubs, and clubs in this nightlife district. A visit to the Historic Crossroads will give you a chance to sip a cold beer while listening to good music. Moreover, catch live blues each night at Hammerstone’s. Some of the nightlife spots in Soulard that you may visit for a memorable night out experience include Bastille, Henry’s in Soulard, Great Grizzly Bear, Social bar & Grill Soulard, and many more. Last, if you are a sports enthusiast, you should visit destinations like Duke’s to watch your favorite team play while taking one of the best cocktails in the region.
# 5 – Central West End
Central West End is another fantastic nightlife district in St. Louis, Missouri. There are multiple nightlife venues and amenities located in strategic places in this neighborhood. Additionally, there are restaurants in this nightlife district that you can visit anytime, day or night, since they operate 24 hours. In addition, there are coffee houses where you can visit late to get hot coffee to keep yourself warm during a cold night out. If you are an art enthusiast and, in this neighborhood, you can visit the world-class art galleries located there during the day.
Moreover, there are fantastic and vintage-style bars with comfortable seats that serve whiskeys, cocktails, and beers that you can visit with friends to have a great time after a long day in the office. If you are a jazz & blues fan, you can catch live performances at Evangeline’s Bistro and Music House. You can go clubbing at Club Viva. There are also LGBTQIA community destinations like Just John Club. Brennan’s, Retreat Gastropub, Pagan Wine bar, Rosie’s Place, and Lazy Tiger are some of the fantastic nightlife venues visiting will make your night out thrilling.
# 4 – Lafayette Square
This neighborhood is known for its impressive colorful Victorian homes, great restaurants, lush gardens, and beautiful boutiques that you can spend your day visiting. This beautiful neighborhood is home to exciting and lively nightlife venues that you should never miss visiting for a memorable night out experience. There are also great venues that you can visit to sip your cold beer while relaxing and listening to cool music playing. Some of the nightlife venues in this neighborhood include Planter’s House, POP, Polite Society Restaurant and Bar, Malt House Cellar, Bailey’s Chocolate Bar, and Sophie’s Artist Lounge. Last, it would be best to never miss the Midnight Pleasures Ice Cream or the alcohol-infused treats such as Boozy Banana Rum Ice Cream with your friends while on your night out during the hot season by visiting Clementine’s Naughty & Nice Creamery.
# 3 – Grand Center Arts District
This neighborhood is known as the epicenter for arts, and it is culturally rich in music such as jazz, classical, blues, and many more. Additionally, there are visual arts in this neighborhood. While in this neighborhood during the day, you can stroll around while having views of the impressive murals. There are great restaurants in this neighborhood that you can visit during a night out to catch a bite before hopping into the pubs, bars, and clubs to get a beer, cocktail, or wine. Some late-night restaurants include The Buttery, Blackthorn, Ranoush, and Brasswell.
Further, this nightlife district features impressive rooftops and patios serving the best wine and cocktails that you should never miss visiting during your night out. You will get a chance to enjoy your drink with friends while having great views of the city and sky at night. Some of the nightlife venues in this neighborhood include Curtain Call Lounge, Probe, and UPBAR.
# 2 – The Grove
The Grove is a beautiful and one of the up-and-coming neighborhoods in St. Louis, Missouri. There are street art and murals in this neighborhood that you can view during the day while taking photographs. As night comes into place, this neighborhood continues to be lively, with plenty of bars and nightclubs along the mile-long stretch, making it an excellent nightlife district.
This beautiful district features eclectic nightlife venues for drinking, live music, and dining. There are also various destinations where you will find live jazz music and cocktails, such as The Dark Room at The Grandel. If you want a late-night happy hour, you should visit Sanctuaria. This neighborhood’s other unique nightlife spots include The Get Down, Rehab Bar and Grill, pagan Wine bar Pop’s Blue Moon, and Handlebar. Furthermore, there are multiple LGBTQIA venues in this nightlife district.
# 1 – Downtown
Downtown is a beautiful nightlife district in St. Louis that features some of the best and most unique spots you should never miss while a night out in the region. Besides, this neighborhood is home to some of the beautiful attractions and landmarks that you can visit. While downtown during the day, you can spend your time visiting and seeing the area while cruising in the St. Louis Riverfront Cruise.
You can also visit the parks and take photos while viewing multiple attractions all over this neighborhood. As the day turns to night, this beautiful neighborhood becomes one of the liveliest nightlife districts in the entire United States, thanks to the various nightlife spots found there. If you want to sip your cold beer while listening to some cool jazz and blues, you should head to BB’S Jazz, Blues, and Soups. There is a wide selection of beers and a food menu that you can take during your night out before getting to the dancefloor to release steam.
Further, there are live performances by artists in various nightlife spots in Downtown St. Louis. You may spend your night sipping beer and having fantastic views of the city on the rooftop at Three Sixty. Get a chance to try all the oysters by visiting Broadway Oyster Bar during your night out. Some of the impressive nightlife spots that visiting will make your night out in this nightlife district memorable include The Crack Fox, The Honky Tonk STL, Thaxton Speakeasy, and The House of Soul. Finally, if you are a sports enthusiast, you can catch your favorite team playing while sipping local beers at Brewhouse Historical Sports Bar.